If you have a particular reaction in mind and wish to know how to achieve it, you can draw a complete reaction, including both reactant and product structures.
Mapping Reactants to Products
If you wish the chemistry to occur at a particular place in the structure, you can map atoms from reactant to product. This tells the database that the atom marked in the reactant corresponds to the marked atom in the product and allows you to set reaction centers (and avoid unwanted reaction centers).
To create a substance or break a particular bond without having a complete reaction
Setting Bonds to Be Broken or Formed
Use the Query Builder to combine text and structure searching
The form-based search is done from the Query Builder option in the main menu
The search Properties bar at the top allow the user to search within all of the forms and fields options.
Fields Search: The fielded search makes available all possible reaction fields. It can be used in the same way that you searched for properties,