1751- A group led by Benjamin Franklin establishes the Academy and Charitable School in the Province of Philadelphia
1755- School is renamed to, "College of Philadelphia"
Spring 1765- John Morgan establishes the first medical school in America (known today as Perelman School of Medicine at Penn); William Shippen, Jr. becomes its first professor (Morgan and Shippen argued their entire lives over whether Morgan started the school, or whether they deserve dual credit)
August 1, 1769- Rush is officially named the first professor of chemistry at the College of Philadelphia
1776- Rush, as recently elected member of the Continental Congress, joins its medical committee
1777- Rush publishes treatise on preventive medicine in the military; soon after named Surgeon General of the Middle Department for Revolutionary War
1778- Rush is forced to resign as Surgeon General by his mentor/tormentor William Shippen, Jr. and returns to post-occupation Philadelphia and resumes his medical practice
1780- Rush begins teaching chemistry again at the College of Philadelphia Medical School
1783- Rush joins medical staff at Pennsylvania Hospital
1789- Rush's American mentor John Morgan dies & Rush becomes the top doctor in Philadelphia, stops lecturing about chemistry, and starts teaching clinical medicine; Publishes the first of many editions of his medical text "Medical Inquiries and Observation"
1791- College of Philadelphia and the University of the State of Pennsylvania combine into the University of Pennsylvania; Rush becomes head of the medical school
1801- Rush publishes "Six introductory lectures, to courses of lectures, upon the institutes and practice of medicine"
November 2, 1807- Rush gives a lecture titled "On the Duty and Advantages of Studying the Diseases of Domestic Animals" at the University of Pennsylvania medical school that will inspire the founding of its School of Veterinary Medicine
January 24, 1811- Rush publishes "Sixteen introductory lectures, to courses of lectures upon the institutes and practice of medicine"
1811- Rush consults with John and Abigail Adams about treatment of their daughter Nabby's breast cancer
Classes at Penn were first held at Surgeon's Hall (on 5th and Walnut St.). The reaction Rush had when he first walked into the building was engrossed, and sometimes overwhelmed. He felt a different kind of environment from his professorship in chemistry.
Each fall, Rush was expected to write and deliver the Introductory Lecture to courses of Lectures upon the Institutes and Practice of Medicine, where Rush wrote about an important and medically inspirational topic. There were also his writings, practices, and memorization that appeared in front of his students. He had to turn down invitations, including Thomas Jefferson's, due to working on his lectures.