Skip to main content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

Systematic Reviews: Tools for Data

This guide is intended to provide related information for the users who prepare to write systematic reviews.

Tools for Managing Data

Systematic Review Toolbox

A resource to identify software tools for various steps in the systematic review process. It is a community-driven, searchable, web-based catalogue of tools that support the systematic review process across multiple domains. 


A free web application that assists systematic review authors in performing literature screening. 


  • Fee-based
  • DistillerSR is an online application designed specifically for the screening and data extraction phases of a systematic review.
  • The system automatically handles promotion and exclusion based on your form design
  • Export data to any spreadsheet or database software
  • Easy protocol changes, the system can re-evaluate all user responses in seconds


Software for semi-automatic citation screening. The web-based annotation tool, currently in beta version, allows project leads to import the citations that are to be screened for a review from either RefMan or Pubmed. 

Export references from EndNote to Abstrackr


Covidence is "the primary screening and data extraction tool for Cochrane authors. Its support of key steps in the Cochrane Review process, cush as citation screening and Risk of bias assessment, and improved links with RevMan make the review writing process more efficient."


This tool "facilitates the entire review process, from protocol development, team management, study selection, critical appraisal, data extraction, data synthesis and writing systematic review report". It support a number of review types. 

UPenn faculty, staff, and students can access freely this tool via Ovid platform, e.g., Ovid Medline, Ovid JBI.

Systematic Review Data Repository (SRDR)

From AHRQ, the Systematic Review Data Repository (SRDR) is a powerful and easy-to-use tool for the extraction and management of data for systematic review or meta-analysis. It is also an open and searchable archive of systematic reviews and their data.


"You can use RevMan for protocols and full reviews. It is most useful when you have formulated the question for the review, and allows you to prepare the text, build the tables showing the characteristics of studies and the comparisons in the review, and add study data. It can perform meta-analyses and present the results graphically." 

Download RevMan


This is completely open-source, cross-platform software for advanced meta-analysis.


ICF International created the DRAGON database to facilitate the development of comprehensive risk assessments that require systematic review and synthesis of a large database of literature, including toxicologic, epidemiologic, and in vitro studies. DRAGON was specifically developed to meet emerging goals in risk assessment, including:

  • Systematic review of literature
  • Complete documentation of all decisions
  • Flexible data entry forms and fields that capture vastly different study designs
  • Unified data entry scheme to allow sharing among different organizations and groups
  • Centralized management capabilities to track different tasks in the overall work flow
  • Modular structure that can evolve as needs emerge

DRAGON currently consists of three modules that support data extraction from animal toxicology studies, human epidemiology studies, and in vitro studies and three additional modules used for literature categorization, study quality review, and assessment management. 


HAWC (Health Assessment Workspace Collaborative) is one of the software tools the US Office of Health Assessment and Translation is using to help manage systematic review and data display. It is a modular web-based interface to facilitate development of human health assessments of chemicals 


The  tool is designed to help those conducting systematic reviews to identify, extract and code information about a particular research study that is to be included in a systematic review. Other tools related are also available. Main tools include

  • Guidelines tools i) the REPOSE Guidelines for the reporting of education research; and ii) detailed sets of questions for coding at the Keywording and Data-extraction stage
  • Data management tools - structures and tools for downloading, storing and managing information on studies used in the reviews
  • EPPI-Reviewer - the EPPI-Centre's online tool for research synthesis
  • MetaLight - which supports the teaching and learning of meta-analysis
  • CCEMG - EPPI-Centre Cost Converter - a tool for assisting with currency conversion.

 Google Search for “Evidence Table” 

Tools for Critical appraisal