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U.S. Food and Drug Administration
These resources, FDA and otherwise, can provide regulatory, safety and cost information on prescirption and OTC drugs and medical devices.
Canadian Agency for Drugs and Technology in Health
Information effectiveness and efficiency of medical devices and drugs
European Medicines Agency
Responsible for the scientific evaluation of medicines developed by pharmaceutical companies for use in the European Union.
Therapeutics Initiative, Canada
Drug Effectiveness Review Project produces systematic literature reviews of drug classes. Documents include Key Questions, Draft Documents and Evidence Tables, and Final Documents and Evidence Tables.