1787: The dispensary, an out patient care center for the vagrant, opens.
1787: Rush helped establish the first American medical society, following the model of the British Royal College of Physicians: the College of Physicians.
October 15, 1789: John Morgan dies & Rush becomes the leader of the medical education community; Rush publishes his first book, Medical Inquiries, and Observations, a collection of his medical essays, which he edits and dramatically expands four times over the next 20 years (link).
November 11, 1789: Rush writes a public letter to the Managers of Pennsylvania Hospital demanding better facilities and better care for patients with mental illness.
1791: College of Philadelphia and the University of the State of Pennsylvania combine into the University of Pennsylvania; Rush becomes head of the medical school.
August-November 1793: Yellow Fever breaks out.
1796: The West Wing of Pennsylvania Hospital opens, exclusively for moral treatment of patients with mental illness and addictions.
1798-99: Rush sues William Cobbett for libel and slander, he attempts to leave Philadelphia by getting a professorship in New York at Columbia, but is thwarted by Alexander Hamilton.